Pharmacology > STUDY GUIDE > NR 565 Exam Final Study Guide( Complete Solution Rated A)Top score (All)
NR 565 Exam Final Study Guide Antacids: weak bases that react with hydrochloric acid to form salt & water. o Used in the treatment of Hyperacidity, GERD, PUD, hyperphosphatemia, and calcium defi c... iency o Contain combinations of metallic cation (aluminum, calcium, magnesium, and sodium) and basic anion (hydroxide, bicarbonate, carbonate, citrate, and trisilicate) Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics o Neutralize Gastric Acidity (causes ^pH of the stomach and duodenal bulb) o Inhibit proteolytic activity of pepsin o Increase lower esophageal sphincter tone o Acid-neutralizing capacity ANC varies between products expressed in mEqs o If ingested in a fasting state, antacids reduce acidity for approximately 20 to 40 minutes o If taken 1 hr after a meal, acidity is reduced for 2 to 3 hrs o A second dose taken after a meal maintains reduced acidity for more than 4 hrs after the meal o The action of antacids occurs locally in the GI tract with minimal absorption, minimal metabolism o ALL antacids are contraindicated in the presence of severe abdominal pain of unknown cause, especially if accompanied by fever -HIGH SODIUM content: pts w/ HTN, CHF, marked renal failure, or on low-sodium diets need to use low sodium preparation -Concurrent administration with enteric-coated drugs, destroys the coating= alters absorption, ^ the risk for adverse effects [Show More]
Last updated: 1 year ago
Preview 1 out of 37 pages
Connected school, study & course
About the document
Uploaded On
Mar 15, 2022
Number of pages
37
Written in
This document has been written for:
Uploaded
Mar 15, 2022
Downloads
0
Views
44
In Browsegrades, a student can earn by offering help to other student. Students can help other students with materials by upploading their notes and earn money.
We're available through e-mail, Twitter, Facebook, and live chat.
FAQ
Questions? Leave a message!
Copyright © Browsegrades · High quality services·