NUR 2063 Pathophysiology Exam 1. All questions with Accurate answers. Graded A+

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What is Pathophysiology - Ans-is the study of what happens when the normal anatomy and physiology go wrong, causing disorder and disease process of the human body. What 4 things does pathophysiolog... y include? - Ans-Etiology, Pathogenesis, Clinical Manifestations, and Treatment Implications What is etiology - Ans-study of causes or reasons for phenomena. Includes Idiopathic conditions that have an unknown origin or cause. What is pathogenesis? - Ans-development or evolution of disease from initial stimulus to the expression of manifestations as time occurs. What are clinical manifestations? - Ans-Signs and symptoms of disorder. What are treatment implications? - Ans-Which combine the etology, pathogenesis, and clinical manifestations to determine the best treatment of condition per individual. What are signs? - Ans-Objective or observed manifestations of disease. What are symptoms? - Ans-Subjective feelings of abnormality in the body. What is objective data - Ans-What you observe and can measure. What are examples of objective data? - Ans-rash, low blood pressure, bleeding What is subjective data? - Ans-What the patient may report to you What are examples of subjective data? - Ans-pain scale, they feel suicidal, fatigued. What is epidemiology? - Ans-study of the patterns of disease involving populations. Based on the spread and contact of diseases in people. What are the levels of disease prevention? - Ans-Primary, Secondary, Tertiary Explain Primary Prevention - Ans-"Preventing"; altering susceptibility or reducing exposure of disease for people. Examples of Primary Prevention - Ans-Vaccinations and Handwashing Explain Secondary Prevention - Ans-"Screening"; early detection, screening, and management of disease to catch disease early before it spreads Examples of Secondary Prevention - Ans-PAP smears for STDs, lab work for HBA1C check, mammogram Explain Tertiary Prevention - Ans-"Treating" and preventing further complications from a disorder or disease after the person has the condition Examples of Tertiary Prevention - Ans-Rehab for hip surgery, relearning ADL's after amputation, Wound care after stroke to prevent pressure ulcers. What is homeostasis? - Ans-a state of equilibrium in which all body systems are in balance and the body is at its most optimal in functioning. Stable. What is allostasis? - Ans-ability to successfully adapt to challenges. It is not a balance but an attempt to adapt to achieve homeostasis. Example: sweating to lower ones body temp. Stages of the General Adaptation Syndrome - Ans-alarm, resistance, exhaustion Explain alarm stage of general adaptation syndrome - Ans-Where the sympathetic nervous system is activated due to stress. Fight or Flight responses are activated and energy is given off by the HPA axis to flee or fight the danger ahead. Blood must be redirected to vital organs in this stage to give the organs energy to work. Explain Resistance stage of general adaptation syndrome - Ans-the activity of the Parasympathetic Nervous system and the endocrine system to return the body to homeostasis. The body should ultimately adapt to the stressor. Explain the exhaustion stage of general adaptation syndrome - Ans-Occurs when the stressor is not removed or overcome in the body. The body can no longer return to homeostasis after prolonged exposure to stressor. It causes the body to be depleted and damaged that can lead to disease or death. What complications can occur if stressors are not resolved from general adaptation syndrome? - Ans-disease can occur physically and mentally, such as anxiety, depression, headaches, insomnia, infection, and heart disease. Name the hormones released during alarm stage of general adaptation syndrome - Ans-Corticotrophin releasing hormone, adrenocorticotrophic hormone, catecholamines( norepinephrine and epinephrine) and cortisol Explain the Role of corticotrophin releasing hormone in alarm stage - Ans-activates the sympathetic nervous system and adrenocorticotropic hormone. Explain the role of norepinephrine during alarm stage - Ans-helps to slow down certain organs such as the GI and GU systems to prepare the body for fight or flight. Explain the role of epinephrine during alarm stage - Ans-Stimulates the fight or flight response by increasing heart rate, bronchodilation of the lungs to increase respirations and amount of air let in, dilates pupils to let more light in, stimulates more glucose to be released. Explain the role of cortisol during alarm stage - Ans-released by ACTH reaching the adrenal cortex, this allows for more energy creation to increase glucose and to reduce inflammation. Suppresses the immune system. Explain the symptoms of a sympathetic nervous system response - Ans-Pupils dilate, salivation inhibited, increase in HR, bronchodilation of airway, increased respirations, glucose release, inhibit GI/GU. Explain the symptoms of a parasympathetic nervous system response - Ans-Pupils constrict, salivation occurs, decreased HR, bronchoconstriction, decreased respiration, GI/GU systems resume action. role of nucleus - Ans-control center of the cell, where DNA and genes are stored, produces mRNA to help build body proteins. Can have 1 or more (liver cells), or none (RBCs). role of mitochondria - Ans-Powerhouse of the cell. Provides energy in ATP, and has its own set of DNA. Role of ribosome - Ans-produces RNA to produce proteins through transcriptions of DNA and translation of RNA into a protein. Can be floating or attached to the Rough ER. Role of lysosomes - Ans-helps breakdown and digest dead cells, organelles, or tissues. Role of rough ER - Ans-folded membranes that move proteins around the cell. Has ribosomes attached to it and helps produce proteins for the cell membranes. role of smooth ER - Ans-ribosomes not attached to smooth ER, helps in the Liver and kidney cells to detoxify, lipid metabolism, synthesis of hormones, and calcium storage. Role of peroxisome - Ans-membrane cells that contain oxidase and catalase to detoxify harmful chemicals, breakdown hydrogen peroxide and filter metabolic wastes. Role of Golgi body - Ans-stacked membranes that act as the sorter and packager for proteins from the ER. Helps move things in and out of cell. Where is extracellular fluid found? - Ans-outside the cell Where is ECF located in the body? - Ans-found in the plasma, lymph, CSF, eye humors, synovial fluid, and the GI secretions. Where is intracellular fluid located? - Ans-inside the cell Where is intracellular fluid found in the body? - Ans-found inside of cells, cytosol. Which electrolytes are found at high concentrations in the ECF? - Ans-sodium, chloride and sodium bicarb. Which electrolytes are found at high concentrations in the ICF - Ans-potassium, magnesium and hydrogen phosphate, and low concentration of sodium and chloride. What is passive transport? - Ans-substances move from a high to low concentration, without energy. Natural What is active transport? - Ans-substances move against their concentration gradient with the help of ATP. Low to High. What is diffusion? - Ans-molecules and ions distributing evenly in the environment. Passive transport used. Goes from high to low concentration and higher the concentration, the faster the spread. What is osmosis? - Ans-allows for fluids to distribute in between the interstitial spaces and intracellular compartments. Water goes low to high. High: high solute concentration to low water concentration Low: low solute concentration [Show More]

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