Principles of Enzymes, Testing and Physiology of LD, CK, AST, ALT, GGT, 5'NT, ALP, ACT, AMY, LIP, and Chymotripsin: This set will test you on the general principles of enzymes as well as the testing and physiology of LD, CK, AST, ALT, GGT, 5'NT, ALP, ACT, AMY, LIP, and chymotripsin.. 20 QnA Plus Explanations.

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Principles of Enzymes, Testing and Physiology of LD, CK, AST, ALT, GGT, 5'NT, ALP, ACT, AMY, LIP, and Chymotripsin 1. What enzyme is primarily found in the cytoplasm of cells and is the most sensitiv... e enzyme to alcoholic hepatitis 1. ALT 2. AST 3. CK 4. GGT 2. Cholinesterase deficiency is very pertinent to what specialty of medicine? 1. Family Medicine 2. Anesthesiology 3. Nephrology 4. Gastroenterology 3. What preanalytical condition will decrease the activity of ALP? 1. Heat 2. Shock 3. Light 4. Refrigeration 4. What does a CK-MB relative index of 8% tell you? 1. 8.30% 2. 21% 3. 5.90% 4. <2% 5. Disseminated Intravascuular Coagulopathy (DIC) will result in which of the following laboratory tests being elevated? 1. ACP 2. AST 3. LD 4. ALP 6. Which test measures prostatic size? 1. GGT 2. 5'-NT 3. ALP 4. PSA 7. GGT is most recognized in its elevations due to what disease? 1. Cholestasis 2. RBCs 3. Placenta previa 4. Bone pathologies 8. How is a coenzyme defined? 1. An inactive enzyme without its cofactor 2. A substance which is essential for the enzymatic reaction to occur, and is not consumed by the reaction 3. The specific location on an enzyme where the reaction takes place 4. A protein that decreases the activation energy of a reaction 9. What is identified during a kinetic assay? 1. First order reaction 2. The change in absorbance over time 3. Zero order reaction 4. The total change in light absorbance 10. Addition of Tartrate to a specimen inhibits an enzyme from what source? 1. Lungs 2. Prostate 3. White Blood Cells 4. Skin 11. The Lineweaver-Burk plot allows us to quickly idenfity inhibitors visually. How do competitive inhibitors appear on the graph? 1. Two diagonal lines that cross at the Y axis 2. Two parallel lines 3. Two diagonal lines that cross at the X axis 4. Two perpendicular lines 12. According to Michaelis and Menten, increasing what decreases the reaction speed? 1. Reducing S 2. Increasing v 3. Reducing S Remember that the only way to slow down these reactions is to decrease the Vmax or the S. 4. Increasing Km 13. What methodology for LD is cheapest and produces NAD+? 1. Wacker Procedure 2. Wroblewski and LaDue Procedure 3. Karmen Procedure 4. DeRitis Procedure 14. What are some preanalytical issues with CK assays? 1. Exposure to light 2. Bilirubinemia 3. Patient age 4. Bed-bound patient 15. What tests are jeopardized by hemolysis? 1. LD 2. GGT 3. AST 4. ALT 16. What is the equation for an enzymatic reaction? 1. E+S = P+E 2. E+PP=ES 3. E+S=SE 4. P+E=EPS 17. What pattern of LD isoenzymes is most likely to be seen with a myocardial infarction? 1. LD1 increased with LD2>LD1 2. LD3 and LD5 are drastically increased with LD4>LD5 3. LD1 and LD2 are greatly increased with LD1>LD2 4. LD2 and LD3 are increased with LD3>LD2 18. What is the associated enzyme with prostate cancer? 1. ACP 2. TRAP 3. CK 4. ALP 19. What is the definition of in "induced fit" or "lock and key" reaction? 1. The active site is immobile and permanent 2. The enzyme changes shape slightly as the substrate binds 3. The enzyme is unable to bind any substrate after acting on a prior substrate 4. Substrates match the corresponding active site perfectly 20. What type of inhibition is occuring when the enzyme is permanently destroyed and the Vmax is decreased along with the Km? 1. Optional inhibition 2. Irreversible inhibition 3. Mandatory inhibition 4. Reversible inhibition [Show More]

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