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Lesson 08 - Osteoarthritis and Total Knee Replacement. Questions and Correct Answers. 2021

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Exercise 1 - Writing Activity This exercise will take approximately 15 minutes to complete. Exercise 1 - Question 1 Briefly describe the pathophysiology of OA. (Hint: See Chapter 18 in your textbo... ok.) The pathophysiology of Osteoarthritis involves a degradation of cartilage and remodeling of bone due to an active response of chondrocytes in the articular cartilage and the inflammatory cells in the surrounding tissuesOA is characterized by progressive deterioration and loss of cartilage in one or more joints (articular cartilage). The normal bluish-white, translucent cartilage becomes opaque and yellowbrown in color. As cartilage and the bone beneath the cartilage begin to erode, the joint space narrows and osteophytes (bone spurs) form. Fissures, calcifications, and ulcerations develop and the cartilage thins. Inflammatory cytokines enhance tissue deterioration. Weight-bearing joints (hips and knees), the vertebral column, and the hands are primarily affected because they are used most often or bear the mechanical stress of body weight. Question 2 0.5 / 1 pts Exercise 1 - Question 2 Which are considered to be causative factors related to the occurrence of primary osteoarthritis? Select all that apply. Corrrreecctt Anssweerr Aging Corrrreecctt!! Genetic changes Corrrreecctt!! Obesity Corrrreecctt!! Joint trauma You Anssweerreed Autoimmune factors [Show More]

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